Human class C GPCR metabotropic glutamate receptor 5 transmembrane domain in complex with the negative allosteric modulator mavoglurant
Organism: Homo sapiens
Model: Experimental
Representation: Coarse-grained
Type: α-helical
Pfam Acc: PF00003
PDB ID: 4OO9
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 38.0 Å
Number of TM segments = 7
Sequence positions:
A: 11-40|46-68|74-100|273-298|310-334|345-370|372-403
Tilt angles:
A - Segment: 11-40 - Tilt: 29.1°
A - Segment: 46-68 - Tilt: 12.1°
A - Segment: 74-100 - Tilt: 9.7°
A - Segment: 273-298 - Tilt: 18.9°
A - Segment: 310-334 - Tilt: 12.5°
A - Segment: 345-370 - Tilt: 24.4°
A - Segment: 372-403 - Tilt: 35.0°
Structural assessment:
MAIDEN score = -93.9296
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]