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Human class C G protein-coupled metabotropic glutamate receptor 1 in complex with a negative allosteric modulator

Organism: Homo sapiens
Model: Experimental
Representation: Coarse-grained
Type: α-helical

Pfam Acc: PF00003
PDB ID: 4OR2


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 32.7 Å

Number of TM segments = 12

Sequence positions:
A: 116-143|151-171|184-206|217-240|268-290|300-324|328-353
B: 482-503|507-529|547-573|578-602|698-721

Tilt angles:
A - Segment: 116-143 - Tilt: 40.6°
A - Segment: 151-171 - Tilt: 19.5°
A - Segment: 184-206 - Tilt: 18.7°
A - Segment: 217-240 - Tilt: 7.9°
A - Segment: 268-290 - Tilt: 7.6°
A - Segment: 300-324 - Tilt: 27.0°
A - Segment: 328-353 - Tilt: 28.4°
B - Segment: 482-503 - Tilt: 16.6°
B - Segment: 507-529 - Tilt: 21.8°
B - Segment: 547-573 - Tilt: 46.7°
B - Segment: 578-602 - Tilt: 30.7°
B - Segment: 698-721 - Tilt: 24.8°


Structural assessment:

MAIDEN score = -72.0986
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]