Human GPR40 bound to allosteric agonist TAK-875
Organism: Homo sapiens
Model: Experimental
Representation: Atomistic
Type: α-helical
Pfam Acc: PF00001
PDB ID: 4PHU
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 25.8 Å
Number of TM segments = 7
Sequence positions:
A: 3-20|47-70|72-102|124-143|182-204|2226-2245|2257-2272
Tilt angles:
A - Segment: 3-20 - Tilt: 33.0°
A - Segment: 47-70 - Tilt: 40.0°
A - Segment: 72-102 - Tilt: 56.1°
A - Segment: 124-143 - Tilt: 27.2°
A - Segment: 182-204 - Tilt: 41.8°
A - Segment: 2226-2245 - Tilt: 12.4°
A - Segment: 2257-2272 - Tilt: 16.9°
Structural assessment:
MAIDEN score = -29.7794
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]