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Human OX2 orexin receptor bound to the insomnia drug Suvorexant

Organism: Homo sapiens
Model: Experimental
Representation: Atomistic
Type: α-helical

Pfam Acc: PF00001
PDB ID: 4S0V


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 39.0 Å

Number of TM segments = 7

Sequence positions:
A: 53-80|90-116|120-150|171-193|210-245|303-332|342-368

Tilt angles:
A - Segment: 53-80 - Tilt: 22.5°
A - Segment: 90-116 - Tilt: 4.2°
A - Segment: 120-150 - Tilt: 25.8°
A - Segment: 171-193 - Tilt: 5.3°
A - Segment: 210-245 - Tilt: 35.7°
A - Segment: 303-332 - Tilt: 21.5°
A - Segment: 342-368 - Tilt: 21.6°


Structural assessment:

MAIDEN score = -43.1462
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]