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Human gamma-Secretase complex

Organism: Homo sapiens
Model: Experimental
Representation: Atomistic
Type: α-helical

Pfam Acc: PF01080
PDB ID: 4UIS


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 27.0 Å

Number of TM segments = 3

Sequence positions:
A: 217-252
B: 222-248|271-463

Tilt angles:
A - Segment: 217-252 - Tilt: 36.6°
B - Segment: 222-248 - Tilt: 44.1°
B - Segment: 271-463 - Tilt: 64.5°


Structural assessment:

MAIDEN score = -19.1067
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]