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Human two pore domain potassium ion channel TREK2 (K2P10.1) in complex with norfluoxetine

Organism: Homo sapiens
Model: Experimental
Representation: Coarse-grained
Type: α-helical

Pfam Acc: PF07885
PDB ID: 4XDK


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 27.0 Å

Number of TM segments = 8

Sequence positions:
A: 4-22|107-131|164-183|216-237
B: 252-271|361-384|408-427|466-487

Tilt angles:
A - Segment: 4-22 - Tilt: 22.4°
A - Segment: 107-131 - Tilt: 43.4°
A - Segment: 164-183 - Tilt: 21.2°
A - Segment: 216-237 - Tilt: 43.0°
B - Segment: 252-271 - Tilt: 21.7°
B - Segment: 361-384 - Tilt: 36.8°
B - Segment: 408-427 - Tilt: 20.6°
B - Segment: 466-487 - Tilt: 42.5°


Structural assessment:

MAIDEN score = -52.5047
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]