Human gamma-secretase complex at 3.4 Å resolution
Organism: Homo sapiens
Model: Experimental
Representation: Atomistic
Type: α-helical
Pfam Acc: PF01080
PDB ID: 5A63
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 23.1 Å
Number of TM segments = 15
Sequence positions:
A: 678-694
C: 13-27|31-52|77-92|116-132|165-182|186-200
B: 83-99|197-214|220-238|245-259|381-396|405-420|434-449
D: 57-72
Tilt angles:
A - Segment: 678-694 - Tilt: 19.9°
C - Segment: 13-27 - Tilt: 17.7°
C - Segment: 31-52 - Tilt: 50.2°
C - Segment: 77-92 - Tilt: 12.2°
C - Segment: 116-132 - Tilt: 27.6°
C - Segment: 165-182 - Tilt: 41.2°
C - Segment: 186-200 - Tilt: 24.6°
B - Segment: 83-99 - Tilt: 25.6°
B - Segment: 197-214 - Tilt: 27.1°
B - Segment: 220-238 - Tilt: 42.5°
B - Segment: 245-259 - Tilt: 19.9°
B - Segment: 381-396 - Tilt: 18.9°
B - Segment: 405-420 - Tilt: 13.9°
B - Segment: 434-449 - Tilt: 32.1°
D - Segment: 57-72 - Tilt: 5.2°
Structural assessment:
MAIDEN score = -111.7238
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]