Human gamma-secretase complex at 3.4 Å resolution
Organism: Homo sapiens
Model: Experimental
Representation: Coarse-grained
Type: α-helical
Pfam Acc: PF01080
PDB ID: 5A63
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 22.2 Å
Number of TM segments = 16
Sequence positions:
A: 642-656
C: 889-905|911-931|954-969|997-1011|1041-1057|1066-1080|1094-1108
B: 671-686|729-745|748-765|776-791|794-807|818-833|846-862
D: 1179-1193
Tilt angles:
A - Segment: 642-656 - Tilt: 3.9°
C - Segment: 889-905 - Tilt: 18.8°
C - Segment: 911-931 - Tilt: 49.4°
C - Segment: 954-969 - Tilt: 19.9°
C - Segment: 997-1011 - Tilt: 16.7°
C - Segment: 1041-1057 - Tilt: 35.4°
C - Segment: 1066-1080 - Tilt: 22.2°
C - Segment: 1094-1108 - Tilt: 7.6°
B - Segment: 671-686 - Tilt: 13.2°
B - Segment: 729-745 - Tilt: 16.9°
B - Segment: 748-765 - Tilt: 34.2°
B - Segment: 776-791 - Tilt: 24.2°
B - Segment: 794-807 - Tilt: 18.7°
B - Segment: 818-833 - Tilt: 24.0°
B - Segment: 846-862 - Tilt: 36.5°
D - Segment: 1179-1193 - Tilt: 3.0°
Structural assessment:
MAIDEN score = -79.9494
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]