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Thermostabilised beta1-adrenoceptor with rationally designed inverse agonist 7-methylcyanopindolol bound

Organism: Meleagris gallopavo
Model: Experimental
Representation: Atomistic
Type: α-helical

Pfam Acc: PF00001
PDB ID: 5A8E


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 38.0 Å

Number of TM segments = 7

Sequence positions:
A: 39-65|78-104|107-137|159-184|199-229|290-316|319-346

Tilt angles:
A - Segment: 39-65 - Tilt: 16.8°
A - Segment: 78-104 - Tilt: 15.7°
A - Segment: 107-137 - Tilt: 29.5°
A - Segment: 159-184 - Tilt: 17.6°
A - Segment: 199-229 - Tilt: 33.8°
A - Segment: 290-316 - Tilt: 20.4°
A - Segment: 319-346 - Tilt: 25.9°


Structural assessment:

MAIDEN score = -116.4360
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]