Lanosterol 14-alpha demethylase with intact transmembrane domain bound to itraconazole
Organism: Saccharomyces cerevisiae
Model: Experimental
Representation: Atomistic
Type: α-helical
Pfam Acc: PF00067
PDB ID: 5EQB
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 21.9 Å
Number of TM segments = 5
Sequence positions:
A: 17-70|106-130|154-183|197-215|309-323
Tilt angles:
A - Segment: 17-70 - Tilt: 65.0°
A - Segment: 106-130 - Tilt: 44.6°
A - Segment: 154-183 - Tilt: 53.1°
A - Segment: 197-215 - Tilt: 43.0°
A - Segment: 309-323 - Tilt: 9.5°
Structural assessment:
MAIDEN score = -35.9081
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]