Gamma secretase in class 1 of the apo- state ensemble
Organism: Homo sapiens
Model: Experimental
Representation: Atomistic
Type: α-helical
Pfam Acc: PF01080
PDB ID: 5FN3
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 24.6 Å
Number of TM segments = 18
Sequence positions:
A: 673-689
C: 7-26|32-52|74-90|119-135|161-178|187-203|214-229
B: 86-101|133-153|160-182|196-213|221-239|245-260|382-397|404-420|434-450
D: 60-75
Tilt angles:
A - Segment: 673-689 - Tilt: 16.3°
C - Segment: 7-26 - Tilt: 16.0°
C - Segment: 32-52 - Tilt: 47.9°
C - Segment: 74-90 - Tilt: 23.1°
C - Segment: 119-135 - Tilt: 26.2°
C - Segment: 161-178 - Tilt: 39.3°
C - Segment: 187-203 - Tilt: 27.4°
C - Segment: 214-229 - Tilt: 4.6°
B - Segment: 86-101 - Tilt: 11.9°
B - Segment: 133-153 - Tilt: 43.1°
B - Segment: 160-182 - Tilt: 44.6°
B - Segment: 196-213 - Tilt: 37.3°
B - Segment: 221-239 - Tilt: 33.6°
B - Segment: 245-260 - Tilt: 14.9°
B - Segment: 382-397 - Tilt: 29.7°
B - Segment: 404-420 - Tilt: 25.6°
B - Segment: 434-450 - Tilt: 25.6°
D - Segment: 60-75 - Tilt: 7.0°
Structural assessment:
MAIDEN score = -157.2631
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]