Gamma secretase in class 1 of the apo- state ensemble
Organism: Homo sapiens
Model: Experimental
Representation: Coarse-grained
Type: α-helical
Pfam Acc: PF01080
PDB ID: 5FN3
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 22.5 Å
Number of TM segments = 18
Sequence positions:
A: 643-658
C: 961-976|981-1002|1026-1041|1067-1082|1114-1129|1136-1150|1167-1181
B: 671-686|724-741|748-766|787-802|806-825|834-848|865-878|889-904|917-933
D: 1249-1264
Tilt angles:
A - Segment: 643-658 - Tilt: 8.8°
C - Segment: 961-976 - Tilt: 19.4°
C - Segment: 981-1002 - Tilt: 47.8°
C - Segment: 1026-1041 - Tilt: 12.1°
C - Segment: 1067-1082 - Tilt: 15.2°
C - Segment: 1114-1129 - Tilt: 27.1°
C - Segment: 1136-1150 - Tilt: 20.9°
C - Segment: 1167-1181 - Tilt: 4.4°
B - Segment: 671-686 - Tilt: 12.3°
B - Segment: 724-741 - Tilt: 42.0°
B - Segment: 748-766 - Tilt: 41.2°
B - Segment: 787-802 - Tilt: 21.3°
B - Segment: 806-825 - Tilt: 43.0°
B - Segment: 834-848 - Tilt: 18.0°
B - Segment: 865-878 - Tilt: 15.8°
B - Segment: 889-904 - Tilt: 18.3°
B - Segment: 917-933 - Tilt: 33.8°
D - Segment: 1249-1264 - Tilt: 8.9°
Structural assessment:
MAIDEN score = -114.3220
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]