Gamma secretase in class 2 of the apo- state ensemble
Organism: Homo sapiens
Model: Experimental
Representation: Atomistic
Type: α-helical
Pfam Acc: PF01080
PDB ID: 5FN4
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 20.7 Å
Number of TM segments = 16
Sequence positions:
A: 675-689
C: 10-26|35-51|77-90|119-132|164-178|187-201|216-229
B: 86-99|196-211|221-237|246-260|262-396|405-418|434-449
D: 61-74
Tilt angles:
A - Segment: 675-689 - Tilt: 8.6°
C - Segment: 10-26 - Tilt: 14.0°
C - Segment: 35-51 - Tilt: 44.4°
C - Segment: 77-90 - Tilt: 24.8°
C - Segment: 119-132 - Tilt: 25.9°
C - Segment: 164-178 - Tilt: 38.4°
C - Segment: 187-201 - Tilt: 29.2°
C - Segment: 216-229 - Tilt: 9.2°
B - Segment: 86-99 - Tilt: 26.0°
B - Segment: 196-211 - Tilt: 27.9°
B - Segment: 221-237 - Tilt: 43.9°
B - Segment: 246-260 - Tilt: 28.9°
B - Segment: 262-396 - Tilt: 48.2°
B - Segment: 405-418 - Tilt: 26.5°
B - Segment: 434-449 - Tilt: 33.6°
D - Segment: 61-74 - Tilt: 12.1°
Structural assessment:
MAIDEN score = -90.5216
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]