Gamma secretase in class 2 of the apo- state ensemble
Organism: Homo sapiens
Model: Experimental
Representation: Coarse-grained
Type: α-helical
Pfam Acc: PF01080
PDB ID: 5FN4
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 23.4 Å
Number of TM segments = 16
Sequence positions:
A: 642-657
C: 891-907|912-932|957-972|998-1013|1043-1060|1067-1082|1096-1111
B: 671-686|729-746|748-767|776-792|796-809|820-836|848-863
D: 1181-1195
Tilt angles:
A - Segment: 642-657 - Tilt: 11.7°
C - Segment: 891-907 - Tilt: 18.1°
C - Segment: 912-932 - Tilt: 43.4°
C - Segment: 957-972 - Tilt: 12.5°
C - Segment: 998-1013 - Tilt: 11.2°
C - Segment: 1043-1060 - Tilt: 31.0°
C - Segment: 1067-1082 - Tilt: 17.5°
C - Segment: 1096-1111 - Tilt: 3.9°
B - Segment: 671-686 - Tilt: 12.1°
B - Segment: 729-746 - Tilt: 18.6°
B - Segment: 748-767 - Tilt: 37.6°
B - Segment: 776-792 - Tilt: 34.7°
B - Segment: 796-809 - Tilt: 17.4°
B - Segment: 820-836 - Tilt: 27.3°
B - Segment: 848-863 - Tilt: 35.6°
D - Segment: 1181-1195 - Tilt: 2.8°
Structural assessment:
MAIDEN score = -92.6297
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]