Gamma secretase in class 3 of the apo- state ensemble
Organism: Homo sapiens
Model: Experimental
Representation: Atomistic
Type: α-helical
Pfam Acc: PF01080
PDB ID: 5FN5
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 25.5 Å
Number of TM segments = 15
Sequence positions:
A: 668-685
C: 3-22|35-55|70-90|121-139|155-174|191-207|209-225
B: 85-102|197-215|220-238|245-262|380-398|403-421
D: 58-74
Tilt angles:
A - Segment: 668-685 - Tilt: 14.4°
C - Segment: 3-22 - Tilt: 16.8°
C - Segment: 35-55 - Tilt: 40.7°
C - Segment: 70-90 - Tilt: 33.0°
C - Segment: 121-139 - Tilt: 24.4°
C - Segment: 155-174 - Tilt: 33.9°
C - Segment: 191-207 - Tilt: 31.2°
C - Segment: 209-225 - Tilt: 19.7°
B - Segment: 85-102 - Tilt: 23.1°
B - Segment: 197-215 - Tilt: 29.4°
B - Segment: 220-238 - Tilt: 30.1°
B - Segment: 245-262 - Tilt: 20.4°
B - Segment: 380-398 - Tilt: 28.3°
B - Segment: 403-421 - Tilt: 29.4°
D - Segment: 58-74 - Tilt: 9.3°
Structural assessment:
MAIDEN score = -147.2011
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]