Gamma secretase in class 3 of the apo- state ensemble
Organism: Homo sapiens
Model: Experimental
Representation: Coarse-grained
Type: α-helical
Pfam Acc: PF01080
PDB ID: 5FN5
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 20.1 Å
Number of TM segments = 16
Sequence positions:
A: 638-651
C: 894-908|922-939|960-974|1009-1022|1045-1059|1078-1091|1097-1110
B: 684-697|740-754|761-775|786-799|807-822|830-844|856-870
D: 1184-1197
Tilt angles:
A - Segment: 638-651 - Tilt: 20.9°
C - Segment: 894-908 - Tilt: 24.7°
C - Segment: 922-939 - Tilt: 45.5°
C - Segment: 960-974 - Tilt: 25.6°
C - Segment: 1009-1022 - Tilt: 20.2°
C - Segment: 1045-1059 - Tilt: 27.5°
C - Segment: 1078-1091 - Tilt: 28.2°
C - Segment: 1097-1110 - Tilt: 9.9°
B - Segment: 684-697 - Tilt: 18.7°
B - Segment: 740-754 - Tilt: 32.2°
B - Segment: 761-775 - Tilt: 33.5°
B - Segment: 786-799 - Tilt: 26.8°
B - Segment: 807-822 - Tilt: 42.1°
B - Segment: 830-844 - Tilt: 31.7°
B - Segment: 856-870 - Tilt: 44.3°
D - Segment: 1184-1197 - Tilt: 16.9°
Structural assessment:
MAIDEN score = -64.1022
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]