Overview



Nucleotide ID [c.1092G>C;1095_1140del]
Protein ID p.K385Mfs*47
Mutation Complex
Type Type 1-like
Class Class A
Category Type 11
COSMIC #NA
Pathologie Essential thrombocythaemia


Structure

# PSIPRED HFORMAT (PSIPRED V4.0)


Conf: 935765026029999999999999999999999999999944999999439999982021


Pred: CHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH


  AA: AAEKQMKDKQDEDQRQRTRRMMRTKMRMRRMRRTRRKMRRKMSPARPRTSCREACLQGWT


              10        20        30        40        50        60


Conf: 39


Pred: CC


  AA: EA

References

PMIDCitation
24325356Klampfl T, Gisslinger H, Harutyunyan AS, et al. Somatic mutations of calreticulin in myeloproliferative neoplasms. N Engl J Med. 2013.369(25):2379-2390. doi:10.1056/NEJMoa1311347
29424450Lasho TL, Finke CM, Tischer A, Pardanani A, Tefferi A. Mayo CALR mutation type classification guide using alpha helix propensity. Am J Hematol. 2018.93(5):E128-E129. doi:10.1002/ajh.25065