Overview



Nucleotide ID c.1104_1155del
Protein ID p.E369Rfs*44
Mutation Deletion
Type Type 1-like
Class Class A
Category Type 18
COSMIC #NA
Pathologie Essential thrombocythaemia


Structure

# PSIPRED HFORMAT (PSIPRED V4.0)


Conf: 935764027549999999999999999999999999994399999832999998213129


Pred: CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC


  AA: AAEKQMKDKQDEEQRLKRMMRTKMRMRRMRRTRRKMRRKMSPARPRTSCREACLQGWTEA


              10        20        30        40        50        60

References

PMIDCitation
24325356Klampfl T, Gisslinger H, Harutyunyan AS, et al. Somatic mutations of calreticulin in myeloproliferative neoplasms. N Engl J Med. 2013.369(25):2379-2390. doi:10.1056/NEJMoa1311347
29424450Lasho TL, Finke CM, Tischer A, Pardanani A, Tefferi A. Mayo CALR mutation type classification guide using alpha helix propensity. Am J Hematol. 2018.93(5):E128-E129. doi:10.1002/ajh.25065