Overview



Nucleotide ID c.1121_1148del
Protein ID p.K374Rfs*47
Mutation Deletion
Type Type other
Class Class C (C1)
Category #NA
COSMIC COSV57130174
Pathologie Essential thrombocythaemia


Structure

# PSIPRED HFORMAT (PSIPRED V4.0)


Conf: 935764016679999999999999999999999999999999999943999998329999


Pred: CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH


  AA: AAEKQMKDKQDEEQRLKEEEEDRTRRMMRTKMRMRRMRRTRRKMRRKMSPARPRTSCREA


              10        20        30        40        50        60


Conf: 98203129


Pred: HHHHHHCC


  AA: CLQGWTEA

References

PMIDCitation
24791854Tefferi A, Wassie EA, Lasho TL, et al. Calreticulin mutations and long-term survival in essential thrombocythemia. Leukemia. 2014.28(12):2300-2303. doi:10.1038/leu.2014.148
29424450Lasho TL, Finke CM, Tischer A, Pardanani A, Tefferi A. Mayo CALR mutation type classification guide using alpha helix propensity. Am J Hematol. 2018.93(5):E128-E129. doi:10.1002/ajh.25065