Overview



Nucleotide ID c.1108_1177del
Protein ID p.E370Rfs*37
Mutation Deletion
Type Type 1-like
Class Class A
Category #NA
COSMIC COSV57120526
Pathologie Essential thrombocythaemia


Structure

# PSIPRED HFORMAT (PSIPRED V4.0)


Conf: 935765027769999999999999999999994499999832999998213129


Pred: CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC


  AA: AAEKQMKDKQDEEQRLKERMRRMRRTRRKMRRKMSPARPRTSCREACLQGWTEA


              10        20        30        40        50

References

PMIDCitation
24325359Nangalia J, Massie CE, Baxter EJ, et al. Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2. N Engl J Med. 2013.369(25):2391-2405. doi:10.1056/NEJMoa1312542
29424450Lasho TL, Finke CM, Tischer A, Pardanani A, Tefferi A. Mayo CALR mutation type classification guide using alpha helix propensity. Am J Hematol. 2018.93(5):E128-E129. doi:10.1002/ajh.25065