The protein contains 314 amino acids for an estimated molecular weight of 35878 Da.
No function (updated: March 4, 2015)
Protein identification was indicated in the following studies:
The following articles were analysed to gather the proteome content of erythrocytes.
The gene or protein list provided in the studies were processed using the ID mapping API of Uniprot in September 2018. The number of proteins identified and mapped without ambiguity in these studies is indicated below.
Only Swiss-Prot entries (reviewed) were considered for protein evidence assignation.
Publication | Identification 1 | Uniprot mapping 2 | Not mapped / Obsolete | TrEMBL | Swiss-Prot |
---|---|---|---|---|---|
Goodman (2013) | 2289 (gene list) | 2278 | 53 | 20599 | 2269 |
Lange (2014) | 1234 | 1234 | 7 | 28 | 1224 |
Hegedus (2015) | 2638 | 2622 | 0 | 235 | 2387 |
Wilson (2016) | 1658 | 1528 | 170 | 291 | 1068 |
d'Alessandro (2017) | 1826 | 1817 | 2 | 0 | 1815 |
Bryk (2017) | 2090 | 2060 | 10 | 108 | 1942 |
Chu (2018) | 1853 | 1804 | 55 | 362 | 1387 |
1 as available in the article and/or in supplementary material
2 uniprot mapping returns all protein isoforms as one entry
The compilation of older studies can be retrieved from the Red Blood Cell Collection database.
The data and differentiation stages presented below come from the proteomic study and analysis performed by our partners of the GReX consortium, more details are available in their published work.
This protein is annotated as membranous in Gene Ontology, is annotated as membranous in UniProt.
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Variant | Description |
---|---|
Hy1 and Hy2 | |
Jo(a) | |
dbSNP:rs28362799 | |
dbSNP:rs28362800 | |
Do(b), Hy1 and Hy2 | |
Hy1 |
The reference OMIM entry for this protein is 110600
The reference OMIM entry for this protein is 616060
A number sign (#) is used with this entry because the Dombrock (DO) blood group system is based on variation in the gene encoding ADP-ribosyltransferase-4 (ART4; 110600) on chromosome 12p12.3.
July 2, 2021: Protein entry updated
Automatic update: OMIM entry 110600 was added.
July 2, 2021: Protein entry updated
Automatic update: OMIM entry 616060 was added.
April 11, 2021: Protein entry updated
Automatic update: OMIM entry 110600 was added.
April 11, 2021: Protein entry updated
Automatic update: OMIM entry 616060 was added.
Feb. 17, 2021: Protein entry updated
Automatic update: OMIM entry 110600 was added.
Feb. 17, 2021: Protein entry updated
Automatic update: OMIM entry 616060 was added.
Oct. 21, 2020: Protein entry updated
Automatic update: OMIM entry 110600 was added.
Oct. 21, 2020: Protein entry updated
Automatic update: OMIM entry 616060 was added.
Aug. 25, 2020: Protein entry updated
Automatic update: OMIM entry 110600 was added.
Aug. 25, 2020: Protein entry updated
Automatic update: OMIM entry 616060 was added.
June 30, 2020: Protein entry updated
Automatic update: OMIM entry 110600 was added.
June 30, 2020: Protein entry updated
Automatic update: OMIM entry 616060 was added.
April 26, 2020: Protein entry updated
Automatic update: OMIM entry 110600 was added.
April 26, 2020: Protein entry updated
Automatic update: OMIM entry 616060 was added.
March 4, 2020: Protein entry updated
Automatic update: OMIM entry 110600 was added.
March 4, 2020: Protein entry updated
Automatic update: OMIM entry 616060 was added.
Jan. 23, 2020: Protein entry updated
Automatic update: OMIM entry 110600 was added.
Jan. 23, 2020: Protein entry updated
Automatic update: OMIM entry 616060 was added.
Dec. 3, 2019: Protein entry updated
Automatic update: OMIM entry 616060 was added.
Dec. 3, 2019: Protein entry updated
Automatic update: OMIM entry 110600 was added.
Oct. 28, 2019: Protein entry updated
Automatic update: OMIM entry 110600 was added.
Oct. 28, 2019: Protein entry updated
Automatic update: OMIM entry 616060 was added.
Sept. 22, 2019: Protein entry updated
Automatic update: OMIM entry 110600 was added.
Sept. 22, 2019: Protein entry updated
Automatic update: OMIM entry 616060 was added.
Aug. 20, 2019: Protein entry updated
Automatic update: OMIM entry 616060 was added.
Aug. 20, 2019: Protein entry updated
Automatic update: OMIM entry 110600 was added.
July 5, 2019: Protein entry updated
Automatic update: OMIM entry 110600 was added.
July 5, 2019: Protein entry updated
Automatic update: OMIM entry 616060 was added.
June 7, 2019: Protein entry updated
Automatic update: OMIM entry 110600 was added.
June 7, 2019: Protein entry updated
Automatic update: OMIM entry 616060 was added.
May 12, 2019: Protein entry updated
Automatic update: OMIM entry 110600 was added.
May 12, 2019: Protein entry updated
Automatic update: OMIM entry 616060 was added.
Jan. 21, 2019: Protein entry updated
Automatic update: OMIM entry 110600 was added.
Jan. 21, 2019: Protein entry updated
Automatic update: OMIM entry 616060 was added.
Nov. 17, 2018: Protein entry updated
Automatic update: OMIM entry 110600 was added.
Nov. 17, 2018: Protein entry updated
Automatic update: OMIM entry 616060 was added.
Oct. 19, 2018: Protein entry updated
Automatic update: OMIM entry 110600 was added.
Oct. 19, 2018: Protein entry updated
Automatic update: OMIM entry 616060 was added.
Oct. 2, 2018: Protein entry updated
Automatic update: OMIM entry 110600 was added.
Oct. 2, 2018: Protein entry updated
Automatic update: OMIM entry 616060 was added.
July 7, 2018: Protein entry updated
Automatic update: OMIM entry 110600 was added.
July 7, 2018: Protein entry updated
Automatic update: OMIM entry 616060 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 110600 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 616060 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 110600 was added.
July 5, 2018: Protein entry updated
Automatic update: OMIM entry 616060 was added.
July 4, 2018: Protein entry updated
Automatic update: OMIM entry 110600 was added.
July 4, 2018: Protein entry updated
Automatic update: OMIM entry 616060 was added.
July 2, 2018: Protein entry updated
Automatic update: OMIM entry 110600 was added.
July 2, 2018: Protein entry updated
Automatic update: OMIM entry 616060 was added.
May 27, 2018: Protein entry updated
Automatic update: OMIM entry 110600 was added.
May 27, 2018: Protein entry updated
Automatic update: OMIM entry 616060 was added.
April 27, 2018: Protein entry updated
Automatic update: OMIM entry 110600 was added.
April 27, 2018: Protein entry updated
Automatic update: OMIM entry 616060 was added.
Feb. 2, 2018: Protein entry updated
Automatic update: Uniprot description updated
Dec. 19, 2017: Protein entry updated
Automatic update: Uniprot description updated
Nov. 23, 2017: Protein entry updated
Automatic update: Uniprot description updated
March 25, 2017: Additional information
No protein expression data in P. Mayeux work for ART4
March 16, 2016: Protein entry updated
Automatic update: OMIM entry 110600 was added.
Feb. 24, 2016: Protein entry updated
Automatic update: model status changed