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Human smoothened 7TM receptor in complex with an antitumor agent

Organism: Homo sapiens
Model: Experimental
Representation: Atomistic
Type: α-helical

Pfam Acc: PF01534
PDB ID: 4JKV


Membrane assignment:

Output PDB file Download

Hydrophobic thickness = 35.0 Å

Number of TM segments = 14

Sequence positions:
A: 229-254|263-287|312-340|358-378|398-424|451-475|515-537
B: 229-254|263-287|312-340|358-378|398-424|451-474|515-537

Tilt angles:
A - Segment: 229-254 - Tilt: 26.5°
A - Segment: 263-287 - Tilt: 35.1°
A - Segment: 312-340 - Tilt: 40.7°
A - Segment: 358-378 - Tilt: 5.3°
A - Segment: 398-424 - Tilt: 21.8°
A - Segment: 451-475 - Tilt: 20.4°
A - Segment: 515-537 - Tilt: 16.4°
B - Segment: 229-254 - Tilt: 26.2°
B - Segment: 263-287 - Tilt: 35.9°
B - Segment: 312-340 - Tilt: 42.2°
B - Segment: 358-378 - Tilt: 6.3°
B - Segment: 398-424 - Tilt: 23.8°
B - Segment: 451-474 - Tilt: 17.7°
B - Segment: 515-537 - Tilt: 15.0°


Structural assessment:

MAIDEN score = -209.8534
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.


Scores for all residue pairs Download




[creation date: Sep-08-2016]