Dopamine transporter elucidates antidepressant mechanism
Organism: Drosophila melanogaster
Model: Experimental
Representation: Coarse-grained
Type: α-helical
Pfam Acc: PF00209
PDB ID: 4M48
Membrane assignment:
Output PDB file Download
Hydrophobic thickness = 32.4 Å
Number of TM segments = 10
Sequence positions:
A: 6-26|44-66|69-115|246-268|272-292|341-366|377-397|399-441|444-472|488-513
Tilt angles:
A - Segment: 6-26 - Tilt: 7.6°
A - Segment: 44-66 - Tilt: 11.2°
A - Segment: 69-115 - Tilt: 48.6°
A - Segment: 246-268 - Tilt: 17.3°
A - Segment: 272-292 - Tilt: 21.7°
A - Segment: 341-366 - Tilt: 43.2°
A - Segment: 377-397 - Tilt: 19.8°
A - Segment: 399-441 - Tilt: 54.1°
A - Segment: 444-472 - Tilt: 42.2°
A - Segment: 488-513 - Tilt: 30.3°
Structural assessment:
MAIDEN score = -51.8478
The MAIDEN score is aimed at assessing the relative quality, i.e. ranking several models (the lower the score, the better the model). It comes here with a color code (red > yellow > green > blue), which is derived from a z-score calculation and indicates the absolute quality.
Scores for all residue pairs Download
[creation date: Sep-08-2016]